Rats and mice, though often overlooked as simple pests, are responsible for spreading a variety of diseases that pose serious health risks to humans and pets. These rodents are not just a nuisance; they can be carriers of harmful pathogens and parasites that can cause illnesses ranging from mild to severe. Understanding the diseases transmitted by rats and mice, how they spread, and how to protect your family and pets is crucial to maintaining a healthy home.
In this blog, we’ll explore the different diseases rats and mice can spread, the symptoms to look out for, and effective prevention and control methods.

Diseases Spread by Rats and Mice to Humans and Pets
1. Leptospirosis
Leptospirosis is a bacterial infection that can be transmitted to humans and animals through direct contact with urine, feces, or contaminated water or soil from infected rats or mice. It’s considered a zoonotic disease, meaning it can be spread from animals to humans.
- Symptoms in Humans: Fever, headache, muscle aches, vomiting, diarrhea, abdominal pain, and jaundice. Severe cases can lead to liver damage, kidney failure, meningitis, or even death.
- Symptoms in Pets: Fever, vomiting, lethargy, abdominal pain, and jaundice. Dogs are particularly susceptible to this disease.
Prevention: To prevent leptospirosis, ensure that food and water sources are kept away from rodent contamination. Make sure pets are up-to-date on vaccines, especially in areas where leptospirosis is more common.
2. Salmonella
Salmonella is a bacterial infection often transmitted through the consumption of food or water contaminated by rodent urine or feces. Mice and rats are common carriers of the bacteria, and their droppings can contaminate surfaces, food, and water supplies.
- Symptoms in Humans: Nausea, vomiting, diarrhea, abdominal cramps, and fever. In severe cases, the infection can lead to dehydration and hospitalization.
- Symptoms in Pets: Vomiting, diarrhea, lethargy, and abdominal discomfort. Pets that ingest contaminated food or water can also suffer from the infection.
Prevention: Practice good hygiene by cleaning up rodent droppings and urine with disinfectants. Store food in rodent-proof containers and keep pet food sealed. Prevent rodent entry into your home by sealing cracks and gaps.
3. Hantavirus
Hantavirus is a deadly virus transmitted through the urine, droppings, or saliva of infected rodents, particularly deer mice. Humans can become infected when they breathe in dust particles contaminated with rodent excrement, or through direct contact with contaminated surfaces.
- Symptoms in Humans: Initial symptoms include fever, fatigue, muscle aches, and headaches. As the infection progresses, it can lead to difficulty breathing, coughing, and fluid in the lungs, which may result in Hantavirus Pulmonary Syndrome (HPS), a potentially fatal condition.
- Symptoms in Pets: While pets are less likely to contract hantavirus, they can still be exposed by eating infected rodents. Symptoms in pets can include lethargy, coughing, and respiratory distress.
Prevention: Avoid contact with rodent droppings or nests. Seal all entry points to prevent rodents from entering the home. If you find rodent droppings or nests, clean them with a disinfectant while wearing gloves and a mask.
4. Rat-Bite Fever
Rat-bite fever is a bacterial infection that can be transmitted through the bite or scratch of an infected rat or mouse. Humans can also contract it by handling rodents or coming into contact with their saliva, urine, or feces.
- Symptoms in Humans: Fever, chills, vomiting, muscle pain, and joint pain. In some cases, the infection can cause rashes, swelling, and septic arthritis.
- Symptoms in Pets: Though rare, pets can contract rat-bite fever if they are bitten by an infected rat. Symptoms in pets may include fever, swollen lymph nodes, and lethargy.
Prevention: Prevent contact with rodents by sealing entry points and keeping food sources out of reach. If you or your pets are bitten or scratched by a rodent, seek medical attention immediately.
5. Plague
The plague, caused by the bacterium Yersinia pestis, is most commonly associated with fleas that infest rats and other rodents. When fleas bite an infected rat and then bite a human or pet, they can transmit the bacteria that causes the plague. Historically, the plague has caused devastating outbreaks, but it is still a concern in some areas.
- Symptoms in Humans: Swollen lymph nodes (buboes), fever, chills, headache, and fatigue. If untreated, it can lead to septicemia and pneumonia.
- Symptoms in Pets: Pets, especially cats, can develop symptoms such as fever, lethargy, swollen lymph nodes, and a loss of appetite if infected with the plague.
Prevention: Prevent flea infestations by treating pets with flea control medications and keeping them indoors. Control rodent populations around your home and seal cracks to prevent rats and mice from entering.
6. Toxoplasmosis
Toxoplasmosis is a parasitic infection that is most commonly transmitted by cats, but rodents can also play a role in the transmission cycle. Rats infected with Toxoplasma gondii can shed the parasite in their urine or feces, which may then be ingested by humans or pets. The infection can also be transmitted through contact with contaminated food, soil, or water.
- Symptoms in Humans: Flu-like symptoms such as fever, fatigue, and swollen lymph nodes. In pregnant women, toxoplasmosis can cause severe complications, including miscarriage or birth defects.
- Symptoms in Pets: Toxoplasmosis is more commonly transmitted through exposure to infected cat feces, but rodents may contribute to the cycle. Symptoms in pets can include fever, lethargy, and in severe cases, neurological symptoms.
Prevention: Avoid contact with rodent droppings, and wash hands thoroughly after handling pets or working in the garden. Keep pet food and water clean and away from potential contamination.
7. Allergic Reactions and Asthma
While not a direct infectious disease, rodents can trigger allergic reactions and asthma symptoms in some people. Rodent dander, saliva, urine, and feces can act as allergens and lead to respiratory issues, particularly in children and those with pre-existing asthma.
- Symptoms in Humans: Sneezing, runny nose, itchy eyes, and coughing. In people with asthma, exposure can worsen symptoms and trigger asthma attacks.
- Symptoms in Pets: Pets, especially cats and dogs, may also suffer from allergies related to rodent exposure, including itchy skin, respiratory issues, or digestive problems.
Prevention: Keep your home clean, seal cracks where rodents can enter, and use air purifiers to reduce allergens. Regularly clean areas where rodent activity is suspected to minimize exposure.
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Preventing Rodent-Borne Diseases
The best way to protect yourself, your family, and your pets from diseases spread by rats and mice is to prevent infestations in the first place. Here are some key steps to reduce the risk:
- Seal Entry Points: Check for and seal any cracks or gaps around windows, doors, and the foundation of your home. Rodents can squeeze through very small openings.
- Keep Food Secure: Store food, including pet food, in sealed containers and clean up spills promptly. Avoid leaving food out overnight.
- Maintain Cleanliness: Regularly clean and disinfect areas where rodents may leave droppings or urine. Pay special attention to kitchens, pantries, and basements.
- Use Rodent Control: Set traps or use rodent repellents to reduce the rodent population around your home. If you notice an infestation, contact a pest control professional.
- Take Precautions When Handling Rodents: If you must handle rats or mice, wear gloves and a mask. Clean areas where rodents have been with disinfectants and dispose of droppings safely.
Conclusion
Rats and mice are more than just a nuisance; they can spread serious diseases that can affect the health of humans and pets alike. By understanding the diseases they carry and taking steps to prevent infestations, you can significantly reduce the risk of illness in your home. If you suspect a rodent problem, take immediate action to eliminate it and protect your family and pets from potential health hazards.
FAQs About Diseases Spread by Rats and Mice
Q1: How can I tell if my pet has been infected by a disease carried by rodents?
Common signs include fever, lethargy, vomiting, loss of appetite, or difficulty breathing. If you suspect your pet has been exposed to rodent-borne diseases, seek veterinary care immediately.
Q2: Can rodents spread diseases to humans through bites?
Yes, some diseases, such as rat-bite fever and the plague, can be transmitted through bites or scratches from infected rodents.
Q3: Are there vaccines for diseases like leptospirosis in pets?
Yes, vaccines are available for leptospirosis in dogs. Consult with your veterinarian to see if this vaccine is appropriate for your pet.
Q4: How can I prevent rodents from entering my home?
Seal cracks and gaps around windows, doors, and foundations. Keep food sealed and stored properly, and set up traps or repellents if needed.
Q5: Can cleaning rodent droppings be dangerous?
Yes, cleaning rodent droppings can expose you to harmful diseases like hantavirus or leptospirosis. Always wear gloves and a mask, and disinfect surfaces afterward.
By following these prevention tips, you can help safeguard your home from the health risks associated with rats and mice.